Human Anti-TPO IgG ELISA Kit
Description
This ELISA (enzyme-linked immunosorbent assay) kit is intended for the quantitative detection of human anti-TPO autoantibody (IgG) in serum. The presence of this autoantibody together with clinical findings and other laboratory tests is a useful aid in the diagnosis of autoimmune thyroid diseases such as Hashimoto's Thyroiditis and Graves' disease.
This ELISA kit is for in-vitro diagnostic use.
Background
Measuring serum autoantibodies against thyroglobulin (Tg) and thyroid peroxidase (TPO) to aid in the detecting and monitoring of autoimmune thyroid disease is a routine practice. Serum anti-TPO autoantibody and anti-Tg autoantibody are fund to be well-correlating with histological changes in Hashimoto's thyroiditis. Clinically, positive anti-TI autoantibody is detected in patients with chronic thyroiditis (70-90%), primary hypothyroidism (~60%), thyrotoxicosis (~50%), and thyroid tumors (~17%). Anti-Tg autoantibodiy is mainly identified in patients with Hashimoto's thyroiditis and Graves' disease (40-70%).
Although ELISA technology has applied to detecting these autoantibodies, the high background in normal populations decrease the clinical diagnostic sensitivity and speicificity. This highly sensitive EDI™ anti-TPO autoantibody ELISA kit was developed with proprietary technology that leads to a very low reaction background in normal populations, and thus increases the clinical diagnostics sensitivity and specificity.
Related Products
Specifications
Catalog no.
Target:
Species
Method
Tests Per Kit
Detection
Sensitivity / LLOD
Dynamic Range
Total Incubation Time
Sample Type
Sample Volume
Storage Temperature
KT-833
Anti-thyroid peroxidase IgG
Human
Sandwich ELISA
96 tests
Colorimetric
1 U / mL
0 - 960 U / mL
1 hour, 50 minutes
Serum
25 µL
2-8 °C
For in-vitro diagnostic use.