Human Anti-Tg IgG ELISA Kit

Description

This ELISA (enzyme-linked immunosorbent assay) kit is intended for the quantitative detection of human anti-Tg autoantibody (IgG) in serum. The presence of this autoantibody together with clinical findings and other laboratory tests is a useful aid in the diagnosis of autoimmune thyroid diseases such as Hashimoto's Thyroiditis and Graves' disease.

This ELISA kit is for in-vitro diagnostic use.

Background

Measuring serum autoantibodies to thyroglobulin (Tg) and thyroid peroxidase (TPO) to aid in the detecting and monitoring of autoimmune thyroid disease is a routine practice. Serum anti-TPO autoantibody and anti-Tg autoantibody are fund to be well-correlating with histological changes in Hashimoto's thyroiditis. Clinically, positive anti-TI autoantibody is detected in patients with chronic thyroiditis (70-90%), primary hypothyroidism (~60%), thyrotoxicosis (~50%), and thyroid tumors (~17%). Anti-Tg autoantibodiy is mainly identified in patients with Hashimoto's thyroiditis and Graves' disease (40-70%).

Although ELISA technology has applied to detecting these autoantibodies, the high background in normal populations decrease the clinical diagnostic sensitivity and speicificity. This highly sensitive EDI™ anti-Tg autoantibody ELISA kit was developed with proprietary technology that leads to a very low reaction background in normal populations, and thus increases the clinical diagnostics sensitivity and specificity.

 

Related Products

KT-833 Human Anti-TPO IgG ELISA Kit

 

Specifications

Catalog no.

Target:

Species

Method

Tests Per Kit

Detection

Sensitivity / LLOD

Dynamic Range

Total Incubation Time

Sample Type

Sample Volume

Storage Temperature

 

KT-832

Antithyroglobulin IgG

Human

Sandwich ELISA

96 tests

Colorimetric

1 U / mL

0 - 1280 U / mL

1 hour, 50 minutes

Serum

25 µL

2-8 °C

For in-vitro diagnostic use.