Fecal MPO Sample Collection Kit
Description
This Fecal MPO Sample Collection Kit is intended to be used with EDI Quantitative Fecal/Urine Myeloperoxidase ELISA Kit (KT-880) for the measurement of MPO in the gut . Each unit in this kit is specifically designed for easy collection of a small amount of stool sample into a pre-filled sample extraction buffer.
For research use only. Not for use in diagnostics procedures.
Background
Myeloperoxidase (MPO) is a specific polymorphonuclear enzyme that is most abundantly expressed in neutrophil granulocytes. It functions in the oxygen-dependent killing of microorganisms and is released from primary granules of neutrophils during acute inflammation. MPO is encoded by the MPO gene, which is about 11kb and composed of 11 introns and 12 exons, located in chromosome 17 (q12-24). The mature 150 kDa MPO protein is a dimer consisting of two 15kDA light chains and two heavy chains in variable degrees of glycosylation.
MPO activity has been found to be linearly related to neutrophil cell count. Since neutrophils play a predominant role in inflammatory and immune reactions in inflammatory bowel disease (IBD) and MPO has been observed both in the intestinal mucosa and gut lavage, the determination of MPO in stool sample provides one of the most sensitive and promising biomarkers in predicting disease severity.
Related Kits
Specifications
Catalog no.
Tests Per Kit
Storage Temperature
KTR-844
50 tubes
2-8 °C for up to 3 days, or -20°C for long term storage. Avoid more than 3 freeze-thaw cycles per specimen.
For research use only. Not for use in diagnostics procedures.