Product Manual (.pdf)

Description

This test kit is intended for use in the quantitative determination of Herceptin levels in human serum or EDTA plasma.

Background

Herceptin (Trasuzumab) is a humanized monoclonal antibody used in cancer treatment for Human Epidermal Growth Factor Receptor 2 (HER2) over-expressing tumors. In the case of these tumors, Herceptin binds to and inhibits tumor growth. Herceptin can also be labeled with various toxins to enhance tumor suppression. Studies have also found that Herceptin targets gastric cancer stem cells characterized by CD90 phenotype.

 This test kit was developed for the measurement of Herceptin (Trastuzumab). However, all the ADC (Antibody Drug Conjugate) drug using Herceptin as carrier antibody can be measured with this assay. These ADC drugs include Trastuzumab emtansine (KADCYLA), Trastuzumab deruxtecan (ENHERTU), etc.

For research use only. Not for use in diagnostics procedures.

Specifications

Catalog no.

Target:

Species:

Method:

Tests Per Kit:

Detection:

Sensitivity / LLOD:

Dynamic Range:

Total Incubation Time:

Sample Type:

Sample Volume:

Storage Temperature:

KT-755

Humanized anti-Her2/neu (Herceptin/trastuzumab)

Human

Sandwich ELISA

96 tests

Colorimetric

0.245 ng/mL

1 - 500 ng/mL

1 hour 50 minutes

serum, EDTA plasma

10 µL

2-8 °C